ACH4 Focused research Areas

Learn more about the ACH4 Member organisations focused research into HIV, HBV, HCV and HTVL-1.

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Statistics

See how many people live with these diseases.

Australia

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Australia

Virology Statistics

  • HIV: 29,460 People Living With HIV
  • HBV : 200,385 People living with chronic Hepatitis B infection
  • HCV: 123,772 People living with Chronic Hepatitis C infection
  • HTLV-1: >2000 People living with HTLV-1, ~120 new notifications annually in NT
Source: Kirby Institute Surveillance Reports, HTLV-1 > Dr. Vicki Krause; NT public health

Regional

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Asia Pacific Region

Virology statistics

  • HIV: 3.6 million People Living With HIV
  • HBV : Est. 18 million People living with chronic Hepatitis B infection
  • HCV: Est. 10 million People living with Chronic Hepatitis C infection
  • HTLV-1: Est 2.5 million
Source: WHO data and statistics, HTLV-1 > derived from the WHO global prevalence data

Global

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Global

Virology Statistics

  • HIV: 38 400 000 People Living With HIV in 2021
  • HBV : Est. 296 million people living with chronic Hepatitis B infection in 2019
  • HCV: Est. 58 million People living with Chronic Hepatitis C infection in 2019
  • HTLV-1: Est.10 million people living with HTLV-1
Source: WHO data and statistics, HTLV-1 > from WHO HTLV factsheet
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Focus Your Learnings

ACH4 researchers focus on four main viruses; Australia’s national response to HIV, Hepatitis B, Hepatitis C and HTLV-1 which are the important sexually transmissible infections and blood borne viruses in Australians, including Aboriginal and Torres Strait Islander populations. The response relies upon a cohesive national virology program provided by ACH4 – the “Australian Centres for HIV, Hepatitis and HTLV-1 Virology”.

Research within ACH4 has long provided seed funding grants for virology and biomedical technology that support the National strategies in Blood Borne Viruses & Sexually Transmissible infections. It provides a forum for communication and collaboration coordinated by an administrative core which organises an annual meeting and distributes grants on the basis of Expression of Interest via Australian research institutions.
The purpose of the Centre is to develop virological and immunological research outcomes of significance to improve the diagnosis, treatment and prevention of HIV, HBV, HCV and HTLV-1 in Australia and in a broader regional and international context.

The Centre is networked across Australia. It aims to attract the very best researchers from many locations to translate their basic research expertise into health care and biotechnology outcomes, to train PhD and early career researchers, to add value to clinical trials by supporting the development of novel and complex diagnostic and prognostic tests, antiviral drugs and vaccines, as well as hold a national conference and contribute to the Australian HIV and Hepatitis conferences throughout, thus encouraging collaboration with researchers within and outside the Centre.

HIV

ACH4 aims to assist in reducing the incidence of HIV through all of its initiatives, including development of novel therapeutic strategies, microbicides, and new approaches to vaccines and better prognostics. It also aims to decrease the number of people with undiagnosed HIV infection through the use of rapid and better diagnostics.

HBV

ACH4 aims to reduce the incidence of Hepatitis B infection by improved surveillance, prognostics and diagnostics including antiviral resistance tests. ACH4 contributed to the establishment of the global "ICE-HBV (International Coalition to Eliminate HBV)" initiative.

HCV

ACH4 aims to reduce the incidence of Hepatitis C and reduce the burden of chronic hepatitis C disease, specifically through the development of novel vaccine strategies, prognostics and novel therapeutics. ACH4 also aims to reduce the burden of disease attributed to chronic Hepatitis C by improved prognostics, therapeutics and evaluation of anti-viral drug resistance.

HTLV-1

ACH4 is working with the National Aboriginal Community Controlled Health Organisation (NACCHO) helping to define and control HTLV-1 in Central Australian indigenous populations by developing diagnostics / prognostics and treatments. International literature focuses on HTLV‑1 as this is more pathogenic than HTLV‑2, with disease outcomes including HTLV‑1‑associated myelopathy and adult T‑cell leukaemia/lymphoma.
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Visit our partner organisations

The 4 year Australian Centre for HIV and Hepatitis Virology Research (ACH4) successful grant application was supported by The Westmead Institute for Medical Research (WIMR), Burnet Institute and The Peter Doherty Institute for Infection and Immunity.

ACH4 are funded by The Australian Government, Department of Health G05055 Blood Borne Viruses (BBV) and Sexually Transmissible Infections (STI) Research Program. 

Supporting materials can be viewed here:

 

ACH4 works with a range of partner organisations including;

    • The Westmead Institute for Medical Research (WIMR), Host Institute. Learn more here
    • Burnet Institute, Learn more here
    • The Doherty Institute, Learn more here
    • Kirby Institute, Learn more here
    • QIMR Berghofer Medical Research Institute, Learn more here
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